Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2646

CAS [899713-86-1]

MF C18H17ClF3N3O3
MW 415.79

  • Purity: 99%
  • Soluble in DMSO



Selective and in vivo active inhibitor for acyl-protein thioesterase APT1 (IC50 values 0.84 µM and >10 µM for APT1 and APT2, respectively; Ki values 280 nM and >10000 nM for WT APT1 and APT2, respectively). A useful tool to study LYPLA/APT mediated protein S-palmitoylation and related pharmacology. In some of the literature, APT1 and APT2 are also identified as lysophospholipases LYPLA1 and LYPLA2 as they were first discovered due to their ability to hydrolyze various lysophospholipids.

KEYWORDS: ML348 | supplier | APT1 inhibitor | ML-348 | CAS [899713-86-1] | S-palmitoylated proteins | APT | acyl-protein thioesterase | LYPLA | APT2 | LYPLA1 | LYPLA2 | lysophospholipids

Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €340.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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