GSK481 - GSK'481

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2608

CAS [1622849-58-4]

MF C21H19N3O4
MW 377.39

  • Purity: 98%
  • Soluble in DMSO



Potent inhibitor of Receptor-interacting serine/threonine-protein kinase 1 (RIPK1 or RIP1; IC50 value 2.8 nM for inhibition of S166 phosphorylation of hWT RIP1) exhibiting a remarkable specificity over >450 other kinases. GSK'481 protects against TNF-induced inflammation and lethal shock.

KEYWORDS: GSK481 | supplier | RIP1 kinase inhibitor | GSK'481 | CAS [1622849-58-4] | Phosphorylation | RIP | inflammation | TNF | RIPK1

Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €335.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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