SR 9243

Based on 19 reference(s) in Google Scholar 9 10 19

Axon 2598

CAS [1613028-81-1]

MF C31H32BrNO4S2
MW 626.62

  • Purity: 99%
  • Soluble in DMSO

SR 9243


LXR inverse agonist that induces LXR-corepressor interaction inhibiting the Warburg effect and lipogenesis in cancer cells by reducing glycolytic and lipogenic gene expression. SR 9243 induced apoptosis in tumors without inducing weight loss, hepatotoxicity, or inflammation. Moreover, SR 9243 may mediate tumor ‘‘unmasking’’ via downregulation of the immune-suppressive effects of LXR ligands within the tumor microenvironment.
Close analogue of GSK 2033 (Axon 2363)

KEYWORDS: SR 9243 | supplier | LXR inverse agonist | SR9243 | CAS [1613028-81-1] | Metabolism | LXR | Inverse agonist | nuclear | Receptors | NR1H | Warburg effect | lipogenesis | cancer cells | glycolytic | lipogenic | gene expression | apoptosis | tumor unmasking

LXR inverse agonist inhibiting the Warburg effect and lipogenesis in cancer cells

Chemical name


Parent CAS No.


Size Unit Price Stock
10 mg €85.00 In Stock
50 mg €255.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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