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ML 297 - VU 0456810

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2436

CAS [1443246-62-5]

MF C17H14F2N4O
MW 328.32

  • Purity: 99%
  • Soluble in DMSO

ML 297

Description

First potent and selective activator of the GIRK potassium channel (EC50 value 0.16 µM for GIRK1/2 activation) with selectivity for GIRK1-containing GIRKs, exhibiting antiepileptic properties in vivo. ML297 showed equal or greater efficacy compared to a clinically active anti-seizure medication,sodium valproate, regardless of whether epilepsy was initiated chemically with PTZ or via electroshock.
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10 mg €95.00 In Stock
50 mg €295.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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