Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2374

CAS [348575-88-2]

MF C15H13N3OS2
MW 315.41

  • Purity: 99%
  • Soluble in 0.1N NaOH(aq) and DMSO



Reversible photoactivated TRPA1 agonist (EC50 value 2 μM) that specifically activates TRPA1, but not TRPV1 or TRPM8. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues, and enables control of motor activity in paralyzed extremities by localized illumination in animals. Optovin-treated animals respond to 387-nm (violet) stimuli but not to 485-nm (blue), 560-nm (green) or longer wavelengths.
Size Unit Price Stock
5 mg €85.00 In Stock
25 mg €285.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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