Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2327

CAS [1361198-79-9]

MF C17H20N6O4
MW 372.38

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO

NEO 212


Novel DNA alkylating agent exhibiting superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo (IC50 values 5-50 µM for cytotoxicity on glioma cell lines). NEO 212 causes DNA damage and cell death much more efficiently than TMZ, because linkage with POH increased its biological half-life and thus provided greater opportunity for placement of cytotoxic DNA lesions.
NEO212 is a conjugate of temozolomide (TMZ, Axon 2326) with the natural product perillyl alcohol (POH) and circumvents TMZ-resistance in multiple cancer cell lines and gliomas.

Size Unit Price Stock
5 mg €110.00 In Stock
25 mg €380.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €160.00 In Stock
2 x 25 mg €560.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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