COMC
Axon N0014
CAS:
106281-45-2
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C11H14O3
- MW: 194.23
Description
Cytotoxic activities
More Information
| Parent CAS No. | 106281-45-2 |
|---|---|
| Chemical Name | (E)-(6-oxocyclohex-1-enyl)methyl but-2-enoate |
| SMILES | C1CC=C(COC(=O)/C=C/C)C(=O)C1 |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | B16 murine melanoma cells proliferation Inhibitor |
References
- Q Zhang et al. Alkylation of nucleic acids by the antitumor agent COMC. Org Lett. 2002 May 2;4(9):1459-62.
- E Joseph et al. Molecular basis of the antitumor activities of 2-crotonyloxymethyl-2-cycloalkenones. J Med Chem. 2003 Jan 2;46(1):194-6.
- E Joseph et al. Selective inhibition of MCF-7(piGST) breast tumors using glutathione transferase-derived 2-methylene-cycloalkenones. J Med Chem. 2005 Oct 20;48(21):6549-52.
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