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CP 346086

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2216

CAS [186390-48-7]

MF C26H22F3N5O
MW 477.48

  • Purity: 99%
  • Soluble in DMSO

CP 346086

Description

Potent microsomal triglyceride transfer protein (MTP, MTTP) inhibitor that inhibits both human and rodent MTP activity (IC50 value 2.0 nM). After a 2 week treatment CP 346086 reduced total and LDL cholesterol and triglycerides by 47%, 72%, and 75%, relative to either individual baselines or placebo, with little change in HDL cholesterol. More potent in MTP inhibition than SLX 4090 and Lomitapide (Juxtapid; IC50 value 8 nM and 5-7 nM respectively).
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Size Unit Price Stock
10 mg €140.00 In Stock
50 mg €540.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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