ONO 5334

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2156

CAS [868273-90-9]

MF C21H34N4O4S
MW 438.58

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in DMSO

ONO 5334

Description

Potent and orally available inhibitor of cathepsin K (Ki values of 0.1 nM, 0.049 nM and 0.85 nM for human, rabbit and rat respectively). ONO 5334 dose depedently suppresses human osteoclast-mediated bone resorption in vitro, and reduced PTHrP-induced increase in plasma calcium with significant effect (86% reduction) after oral administration in TPTX pretreated rats.
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Size Unit Price Stock
2 mg €110.00 In Stock
5 mg €200.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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