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SPD 304

Axon 2143
CAS:  869998-49-2
Purity:  99%
  • Soluble in water and DMSO
  • MF:  C32H32F3N3O2.2HCl
  • MW:  620.53

Description

A cell permeable inhibitor of tumor necrosis factor-α (TNFα, IC50: 22 μM); inhibits TNF-α induced IkB-α depletion in HeLa cells (IC50: 4.6 μM)

More Information

Parent CAS No. 869998-49-2
Chemical Name 6,7-dimethyl-3-((methyl(2-(methyl((1-(3-(trifluoromethyl)phenyl)-1H-indol-3-yl)methyl)amino)ethyl)amino)methyl)-4H-chromen-4-one dihydrochloride
SMILES C1OC2=CC(C)=C(C)C=C2C(=O)C=1CN(C)CCN(C)CC1C2=C(N(C3=CC=CC(C(F)(F)F)=C3)C=1)C=CC=C2.Cl.Cl
MFCD N.A.
InChi InChI=1S/C32H32F3N3O2.2ClH/c1-21-14-28-30(15-22(21)2)40-20-24(31(28)39)18-37(4)13-12-36(3)17-23-19-38(29-11-6-5-10-27(23)29)26-9-7-8-25(16-26)32(33,34)35;;/h5-11,14-16,19-20H,12-13,17-18H2,1-4H3;2*1H
InChiKey GOZMBJCYMQQACI-UHFFFAOYSA-N
CID 16079006
Short Description TNFα inhibitor

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