SPD 304

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2143

CAS [1049741-03-8]

MF C32H32F3N3O2.2HCl
MW 620.53

SPD 304

Description

A cell permeable inhibitor of tumor necrosis factor-α (TNFα, IC50: 22 μM); inhibits TNF-α induced IkB-α depletion in HeLa cells (IC50: 4.6 μM)

Apoptosis Cell Signaling & Oncology Immunology Pain & Inflammation TNF-R1 (CD120) NF-κB Type 1

Cell permeable inhibitor of TNFα

6,7-dimethyl-3-((methyl(2-(methyl((1-(3-(trifluoromethyl)phenyl)-1H-indol-3-yl)methyl)amino)ethyl)amino)methyl)-4H-chromen-4-one dihydrochloride

[869998-49-2]

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Size	Unit Price	Stock
5 mg	€145.00	In Stock
25 mg	€580.00	In Stock

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Axon ID	Name	Description
1507	TMI 005	TACE/MMP inhibitor	€150.00
2300	TIC10 active isomer	Small molecule that transcriptionally induces TRAIL	€125.00
2324	SC 144 hydrochloride	The first-in-class small-molecule gp130 inhibitor	€130.00
2887	DRI-C21045	Inhibitor of the CD40-CD40L costimulatory protein-protein interaction	€125.00
2966	NSC745887	DcR3 inhibitor	€95.00
3166	Pomalidomide	TNFα inhibitor. Immunomodulator.	€60.00
3324	Thalidomide	TNFα inhibitor. Immunomodulator.	€50.00