Bulk Inquiry
Torcetrapib
- CP 529414
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C26H25F9N2O4
- MW: 600.47
Description
Torcetrapib (CP529414) is a cholesteryl ester transfer protein (CETP) inhibitor. It modulates lipoprotein cholesterol transfer and was developed for studying HDL-raising and cardiovascular lipid-modifying pharmacology.
CETP transfers cholesteryl esters from HDL to apoB-containing lipoproteins and influences HDL and LDL cholesterol profiles. Torcetrapib is useful for investigating CETP biology, lipoprotein remodeling and cardiovascular risk mechanisms.
Key Features
- CETP inhibitor
- Modulates HDL and LDL lipoprotein metabolism
- Targets cholesteryl ester transfer between lipoproteins
- Relevant to cardiovascular lipid pharmacology
Applications
- CETP activity assays
- Lipoprotein metabolism research
- HDL cholesterol pathway studies
- Cardiovascular drug-discovery models
More Information
| Parent CAS No. | 262352-17-0 |
|---|---|
| Chemical Name | (2R,4S)-ethyl 4-((3,5-bis(trifluoromethyl)benzyl)(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate |
| extra_info | . |
| SMILES | N1(C(OCC)=O)C2=C(C=C(C(F)(F)F)C=C2)[C@@H](N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C(OC)=O)C[C@H]1CC |&1:16,38,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C26H25F9N2O4/c1-4-18-12-21(19-11-15(24(27,28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30,31)32)10-17(9-14)26(33,34)35/h6-11,18,21H,4-5,12-13H2,1-3H3/t18-,21+/m1/s1 |
| InChiKey | CMSGWTNRGKRWGS-NQIIRXRSSA-N |
| CID | 159325 |
| Short Description | CETP inhibitor |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1962 | Dalcetrapib |
From $148.50 |
| 2043 | Atorvastatin calcium |
From $66.00 |
| 2216 | CP 346086 |
From $154.00 |
| 2276 | Atglistatin |
From $99.00 |
| 2286 | Evacetrapib |
From $137.50 |
| 2506 | BMS 303141 |
From $99.00 |
| 2657 | MGL-3196 |
From $99.00 |
| 4259 | AZD0780 |
From $154.00 |
