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PF 3845
Axon 1711
CAS:
1196109-52-0
Purity:
99%
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C24H23F3N4O2
- MW: 456.46
Description
Highly selective and irreversible fatty acid amide hydrolase (FAAH) inhibitor
More Information
| Parent CAS No. | 1196109-52-0 |
|---|---|
| Chemical Name | N-(pyridin-3-yl)-4-(3-(5-(trifluoromethyl)pyridin-2-yloxy)benzyl)piperidine-1-carboxamide |
| SMILES | N1C=C(NC(=O)N2CCC(CC3C=C(OC4C=CC(C(F)(F)F)=CN=4)C=CC=3)CC2)C=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C24H23F3N4O2/c25-24(26,27)19-6-7-22(29-15-19)33-21-5-1-3-18(14-21)13-17-8-11-31(12-9-17)23(32)30-20-4-2-10-28-16-20/h1-7,10,14-17H,8-9,11-13H2,(H,30,32) |
| InChiKey | NBOJHRYUGLRASX-UHFFFAOYSA-N |
| CID | 25154867 |
| Short Description | FAAH inhibitor |
References
- K Ahn et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chem. Biol. 2009, 16, 411-420.
- L Booker et al. The FAAH Inhibitor PF-3845 Acts in the Nervous System to Reverse Lipopolysaccharide-induced Tactile Allodynia in Mice. Br. J. Pharmacol. 2012, 165(8), 2485-2496.
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