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VU 0152100
- VU 152100
- Soluble in DMSO
- MF: C18H19N3O2S
- MW: 341.43
Description
More Information
| Parent CAS No. | 409351-28-6 |
|---|---|
| Chemical Name | 3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxylic acid 4-methoxy-benzylamide |
| SMILES | C1C(C)=C2C(N)=C(C(NCC3C=CC(OC)=CC=3)=O)SC2=NC=1C |
| MFCD | MFCD02742972 |
| InChi | InChI=1S/C18H19N3O2S/c1-10-8-11(2)21-18-14(10)15(19)16(24-18)17(22)20-9-12-4-6-13(23-3)7-5-12/h4-8H,9,19H2,1-3H3,(H,20,22) |
| InChiKey | MDNWGCQSCGNTKH-UHFFFAOYSA-N |
| CID | 864492 |
| Short Description | PAM of M4 mAChR |
References
- AE Brady et al. Centrally Active Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Ratss. J. Pharmacol. Exp. Ther. 2008, 327(3), 941–953.
- CM Jones. M4 Positive Allosteric Modulators For The Treatment Of Schizophrenia. Grant 1R01MH086601-01 from National Institute Of Mental Health.
- P Jeffrey Conn et al. Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders. Trends in Pharmacological Sciences 2009, 30(3), 148-155.
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