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BMS 232632
- Atazanavir - CGP 73547
- Soluble in DMSO
- MF: C38H52N6O7
- MW: 704.86
Description
Orally active protease inhibitor (PI); antiretrovirals used to treat infection of human immunodeficiency virus (HIV). Also available is Compounds 120 - CTP518, a partially deuterated analog of Atazanavir (Axon 1753) with improved ADME properties.
More Information
| Parent CAS No. | 198904-31-3 |
|---|---|
| Chemical Name | Methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate |
| MFCD | MFCD08435966 |
| Short Description | Protease inhibitor |
References
- P Pyrko. HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress. Cancer Research 2007, 67, 10920–8.
- T Ly & M Ruiz. Prolonged QT interval and torsades de pointes associated with atazanavir therapy Question: Have patients developed Liver stones as a side-effect of this medication?". Clin Infect Dis 2007, 44 (6), e67–8.
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