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Selonsertib

 - GS 4997
Axon 2956
CAS:  1448428-04-3
Purity:  99%
  • Soluble in 0.1N HCl(aq) and DMSO
  • MF:  C24H24FN7O
  • MW:  445.49

Description

Selonsertib is a potent, highly selective, orally available, and ATP-competitive ASK1 inhibitor with a pIC50 value of 8.3.

More Information

Parent CAS No. 1448428-04-3
Chemical Name 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide
SMILES C1(N2C=C(C3CC3)N=C2)C=C(C(=O)NC2C=CC=C(C3=NN=CN3C(C)C)N=2)C(F)=CC=1C
MFCD MFCD29920355
InChi InChI=1S/C24H24FN7O/c1-14(2)32-13-27-30-23(32)19-5-4-6-22(28-19)29-24(33)17-10-21(15(3)9-18(17)25)31-11-20(26-12-31)16-7-8-16/h4-6,9-14,16H,7-8H2,1-3H3,(H,28,29,33)
InChiKey YIDDLAAKOYYGJG-UHFFFAOYSA-N
CID 71245288
Short Description ASK1 inhibitor

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