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ORG 25935
- SCH 900435
Axon 1563
- Parent CAS: 754965-07-6
Purity:
99%
- Soluble in DMSO
- MF: C21H25NO3.HCl
- MW: 375.89
Description
Potent and selective GlyT-1 glycine transporter or reuptake inhibitor; a therapeutic intended for the treatment of neurological disorders
More Information
| Parent CAS No. | 754965-07-6 |
|---|---|
| Chemical Name | rel-[((1R,2S)-6-Methoxy-1-phenyl-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-methyl-amino]-acetic acid hydrochloride |
| MFCD | MFCD19708017 |
| Short Description | GlyT-1 inhibitor |
References
- HH Lidoe et al. The glycine reuptake inhibitor Org 25935 interacts with basal and ethanol-induced dopamine release in rat nucleus accumbens. Alcoholism: Clin. Exp. Res. 2009, 33(7), 1151-1157.
- K Morita et al. Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice. J. Pharmacol. Exp. Ther. 2008, 326(2), 633-645.
- A Molander et al. The glycine reuptake inhibitor Org 25935 decreases ethanol intake and preference in male Wistar rats. Alcohol and Alcoholism (Oxford, United Kingdom) (2007), 42(1), 11-18.
- K Hashimoto. Glycine Transporter Inhibitors as Therapeutic Agents for Schizophrenia. Recent Patents on CNS Drug Discovery, 2006, 1, 43-53.
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