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Loperamide hydrochloride
- Parent CAS: 53179-11-6
- Soluble in DMSO and EtOH
- MF: C29H33ClN2O2.HCl
- MW: 513.5
Description
Loperamide is a peripherally restricted potent μ-opioid receptor (MOR) agonist with a Ki value of 3.3 nM. Loperamide can also inhibit voltage-gated L-type calcium channels and trigger autophagy-dependent cell death as well. Antidiarrheal medicine.
More Information
| Parent CAS No. | 53179-11-6 |
|---|---|
| Chemical Name | 4-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide hydrochloride |
| SMILES | N(C)(C)C(=O)C(C1C=CC=CC=1)(C1C=CC=CC=1)CCN1CCC(O)(C2C=CC(Cl)=CC=2)CC1.Cl |
| MFCD | MFCD00058581 |
| InChi | InChI=1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H |
| InChiKey | PGYPOBZJRVSMDS-UHFFFAOYSA-N |
| CID | 71420 |
| Short Description | u-opioid agonist |
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