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Imiquimod
- R-837 - S26308
Axon 3107
CAS:
99011-02-6
Purity:
99%
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C14H16N4
- MW: 240.3
Description
Imiquimod is a TLR7/TLR8 agonist with immunomodulatory activity.
More Information
| Parent CAS No. | 99011-02-6 |
|---|---|
| Chemical Name | 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine |
| SMILES | C1C2N=C(N)C3N=CN(CC(C)C)C=3C=2C=CC=1 |
| MFCD | MFCD00866946 |
| InChi | InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17) |
| InChiKey | DOUYETYNHWVLEO-UHFFFAOYSA-N |
| CID | 57469 |
| Short Description | TLR7/TLR8 agonist |
References
- DE Spaner et al. Regression of lymphomatous skin deposits in a chronic lymphocytic leukemia patient treated with the Toll-like receptor-7/8 agonist, imiquimod. Leuk Lymphoma. 2005 Jun;46(6):935-9.
- M Chen et al. Efficacy of S26308 against guinea pig cytomegalovirus infection. Antimicrob Agents Chemother. 1988 May;32(5):678-83.
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