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NSC745887
Axon 2966
CAS:
54490-26-5
Purity:
99%
- Soluble in DMSO
- MF: C16H8N2O2
- MW: 260.25
Description
NSC745887 is a DcR3 inhibitor which reduced the cell survival rate and increased the sub-G1 population in dose- and time-dependent manners in glioblastoma multiforme (GBM) cells. Moreover, NSC745887 inhibits the proliferation of various cancers by trapping DNA-topoisomerase cleavage.
More Information
| Parent CAS No. | 54490-26-5 |
|---|---|
| Chemical Name | Naphtho[2,3-f]quinoxaline-7,12-dione |
| SMILES | C1=CC2C(=O)C3C4N=CC=NC=4C=CC=3C(=O)C=2C=C1 |
| MFCD | N.A. |
| InChi | InChI=1S/C16H8N2O2/c19-15-9-3-1-2-4-10(9)16(20)13-11(15)5-6-12-14(13)18-8-7-17-12/h1-8H |
| InChiKey | DGLSEJAACVWJNU-UHFFFAOYSA-N |
| CID | 12567021 |
| Short Description | DcR3 inhibitor |
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