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A-92

Axon 2720
CAS:  1448693-69-3
Purity:  99%
  • Soluble in DMSO
  • MF:  C19H18N10O
  • MW:  402.41

Description

A-92 is a GCN2 inhibitor that inhibits the stress response of general control nonderepressible 2 kinase (GCN2 or EIF2AK4) (IC50 value of <0.3 μM). Possible chemotherapeutic drug for the treatment of cancer.

More Information

Certificate of Analysis (B2)
Material Safety Data Sheet (B2)

Certificate of Analysis

B1

Material Safety Data Sheet

B1
Parent CAS No. 1448693-69-3
Chemical Name 3-(1H-Indazol-6-yl)-N-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine
SMILES O1CCC(N2N=CC(NC3N=C4N(N=NC4=CN=3)C3C=CC4C=NNC=4C=3)=C2)CC1
MFCD N.A.
InChi InChI=1S/C19H18N10O/c1-2-15(7-16-12(1)8-21-25-16)29-18-17(26-27-29)10-20-19(24-18)23-13-9-22-28(11-13)14-3-5-30-6-4-14/h1-2,7-11,14H,3-6H2,(H,21,25)(H,20,23,24)
InChiKey CFNFLNGJQOHNPR-UHFFFAOYSA-N
CID 89720372
Short Description GCN2 inhibitor

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