(Total 26 publication citations up to September 2025)

Lopez-Nieto, M., Sun, Z., Relton, E., Safakli, R., Freibaum, B. D., Taylor, J. P., ... & Locker, N. (2025). Activation of the mitochondrial unfolded protein response regulates the dynamic formation of stress granules. Journal of Cell Science, 138(9), jcs263548.
https://journals.biologists.com/jcs/article/138/9/jcs263548/363301
* A-92 and GSK2606461 from Axon Medchem

Rodschinka, G., Forcelloni, S., Kühner, F. M., Wani, S., Riemenschneider, H., Edbauer, D., ... & Nedialkova, D. D. (2025). Comparative CRISPRi screens reveal a human stem cell dependence on mRNA translation-coupled quality control. Nature Structural & Molecular Biology, 1–15.
https://www.nature.com/articles/s41594-025-01616-3

Haberecht-Müller, S. (2025). Elucidating the DDI2-TCF11/NRF1 axis of proteasome gene activation and its impact on various stress signaling pathways (Doctoral dissertation).
https://epub.ub.uni-greifswald.de/frontdoor/deliver/index/docId/13678/file/Dissertation_Haberecht-Mueller_2025-03-20.pdf
* A-92 and ISrap from Axon Medchem

Safakli, R. N. (2025). Identifying the mechanisms that define the activation of the mitochondrial unfolded protein response in the stressed heart (Doctoral dissertation, University of Surrey).
https://openresearch.surrey.ac.uk/view/pdfCoverPage?instCode=44SUR_INST&filePid=13221439630002346&download=true

Möller, S., Alehashemi, S., Wendlandt, M., Thiel, F. G., de Jesus, A., Papendorf, J. J., ... & MIS-C Consortium. (2025). A De Novo Dominant-Negative PSMB8 Mutation Causes Severe CANDLE/PRAAS Due to Arrested Proteasome Biogenesis.
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5370606

Torres, C. (2024). Modulation de la réplication du VIH-1 et régulation par le SRAS-CoV-2: la kinase GCN2 comme facteur clef de restriction des infections virales (Doctoral dissertation, Université de Bordeaux).
https://theses.hal.science/tel-04972879v1/document

Jordana, M. L. N. (2024). Investigating the interplay between stress granules, mitochondria and viruses (Doctoral dissertation, University of Surrey).
https://openresearch.surrey.ac.uk/view/pdfCoverPage?instCode=44SUR_INST&filePid=13216423120002346&download=true

Zhu, M. M., Dai, J., Dai, Z., Peng, Y., & Zhao, Y. Y. (2024). GCN2 kinase activation mediates pulmonary vascular remodeling and pulmonary arterial hypertension. JCI Insight, 9(20), e177926.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11530134/

Garrec, S. L., Pinel, K., Heraud, C., Ganot, A., Veron, V., Morin, G., ... & Beaumatin, F. (2024). Dissecting the nutritional regulations of a whole amino acid transporter family from a complex genome species: A holistic approach turning weaknesses into strengths. bioRxiv, 2024-10.
https://www.biorxiv.org/content/10.1101/2024.10.11.617833v1.full

Aleksashin, N. A., Chang, S. T. L., & Cate, J. H. (2023). A highly efficient human cell-free translation system. RNA, 29(12), 1960–1972.
https://rnajournal.cshlp.org/content/29/12/1960.short
* A-92 and GSK2606414 from Axon Medchem

Ryder, L., Arendrup, F. S., Martínez, J. F., Snieckute, G., Pecorari, C., Shah, R. A., ... & Bekker-Jensen, S. (2023). Nitric oxide-induced ribosome collision activates ribosomal surveillance mechanisms. Cell Death & Disease, 14(7), 467.
https://www.nature.com/articles/s41419-023-05997-5

Waad Sadiq, Z., Brioli, A., Al-Abdulla, R., Çetin, G., Schütt, J., Murua Escobar, H., ... & Ebstein, F. (2023). Immunogenic cell death triggered by impaired deubiquitination in multiple myeloma relies on dysregulated type I interferon signaling. Frontiers in Immunology, 14, 982720.
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.982720/full
* A-92 and BX-795 from Axon Medchem

Lopez-Nieto, M., Sun, Z., Relton, E., Safakli, R., Freibaum, B. D., Taylor, J. P., ... & Locker, N. (2023). Activation of the mitochondrial unfolded protein response regulates the formation of stress granules. bioRxiv, 2023-10.
https://www.biorxiv.org/content/10.1101/2023.10.26.564187v2.full

Snieckute, G., Genzor, A. V., Vind, A. C., Ryder, L., Stoneley, M., Chamois, S., ... & Bekker-Jensen, S. (2022). Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response. Cell Metabolism, 34(12), 2036–2046.
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(22)00489-2
* A-92 and MK-2408 from Axon Medchem

Torres, C., Garling, A., Taouji, S., Calmels, C., Andreola, M. L., & Métifiot, M. (2021). Targeting the integrated stress response kinase GCN2 to modulate retroviral integration. Molecules, 26(17), 5423.
https://pubmed.ncbi.nlm.nih.gov/34500856/
* A-92 from Axon Medchem

Torres, C., Garling, A., Taouji, S., Calmels, C., Andreola, M. L., & Métifiot, M. (2021). Targeting the integrated stress response kinase GCN2 to modulate retroviral integration. Molecules, 26(17), 5423.
https://www.mdpi.com/1420-3049/26/17/5423
* A-92 from Axon Medchem

Brocard, M., Lu, J., Hall, B., Borah, K., Moller-Levet, C., Georgana, I., ... & Locker, N. (2021). Murine norovirus infection results in anti-inflammatory response downstream of amino acid depletion in macrophages. Journal of Virology, 95(20), e01134-21.
https://journals.asm.org/doi/abs/10.1128/jvi.01134-21

Brocard, M., Lu, J., Hall, B. S., Borah, K., Moller-Levet, C. S., Georgana, I., ... & Locker, N. S. (2021). nsP4 Is a Major Determinant of Alphavirus Replicase Activity and Template Selectivity. Journal of Virology, 95(20).
https://openresearch.surrey.ac.uk/esploro/outputs/journalArticle/Murine-norovirus-infection-results-in-anti-inflammatory/99594822902346

Wu, C. C. C., Peterson, A., Zinshteyn, B., Regot, S., & Green, R. (2020). Ribosome collisions trigger general stress responses to regulate cell fate. Cell, 182(2), 404–416.
https://www.cell.com/cell/fulltext/S0092-8674(20)30693-0
* A-92 and GSK2606414 from Axon Medchem

Brocard, M., Iadevaia, V., Klein, P., Hall, B., Lewis, G., Lu, J., ... & Locker, N. (2020). Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation. PLoS Pathogens, 16(1), e1008250.
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008250

Brocard, M., Ladevaia, V., Klein, P., Hall, B., Lewis, G., Lu, J., ... & Locker, N. (2020). Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation. PLoS Pathogens.
https://openresearch.surrey.ac.uk/esploro/outputs/journalArticle/Norovirus-infection-results-in-eIF2%C3%8E%C2%B1-independent/99511822802346

Vallejo-Gracia, A., Chen, I. P., Perrone, R., Besnard, E., Boehm, D., Battivelli, E., ... & Ott, M. (2020). FOXO1 promotes HIV latency by suppressing ER stress in T cells. Nature Microbiology, 5(9), 1144–1157.
https://www.nature.com/articles/s41564-020-0742-9

Vallejo-Gracia, A., Chen, I. P., Perrone, R., Besnard, E., Boehm, D., Battivelli, E., ... & Ott, M. (2020). FOXO1 promotes HIV latency by suppressing ER stress in T cells. Nature Microbiology, 5(9), 1144–1157.
https://www.biorxiv.org/content/10.1101/2020.04.23.058123v1.full

Samluk, L., Urbanska, M., Kisielewska, K., Mohanraj, K., Kim, M. J., Machnicka, K., ... & Chacinska, A. (2019). Cytosolic translational responses differ under conditions of severe short-term and long-term mitochondrial stress. Molecular Biology of the Cell, 30(15), 1864–1877.
https://www.molbiolcell.org/doi/full/10.1091/mbc.E18-10-0628
* A-92 and CHIR99021 from Axon Medchem

Brocard, M., Iadevaia, V., Klein, P., Hall, B., Lewis, G., Lu, J., ... & Locker, N. (2018). Norovirus infection results in assembly of virus-specific G3BP1 granules and evasion of eIF2α signaling. bioRxiv, 490318.
https://www.biorxiv.org/content/10.1101/490318.abstract

Franchini, D. M., Lanvin, O., Tosolini, M., de Campaigno, E. P., Cammas, A., Péricart, S., ... & Fournié, J. J. (2019). Microtubule-driven stress granule dynamics regulate inhibitory immune checkpoint expression in T cells. Cell Reports, 26(1), 94–107.
https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31925-9
* A-92 and GSK2606414 from Axon Medchem