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BI-1015550
- Nerandomilast
- Optical Purity: 100% e.e.
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C20H25ClN6O2S
- MW: 448.97
Description
BI-1015550 is a selective and orally active PDE4 inhibitor showing a preferential enzymatic inhibition of PDE4B (IC50 value of 10 nM).
More Information
| Parent CAS No. | 1423719-30-5 |
|---|---|
| Chemical Name | (R)-5-(4-(5-Chloro-2-pyrimidinyl)-1-piperidyl)-7-(1-(hydroxymethyl)cyclobutylamino)-1λ4-thia-4,6-diaza-1-indanone |
| SMILES | N1=C(N2CCC(C3=NC=C(Cl)C=N3)CC2)N=C(NC2(CCC2)CO)C2[S@](=O)CCC1=2 |&1:25,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C20H25ClN6O2S/c21-14-10-22-17(23-11-14)13-2-7-27(8-3-13)19-24-15-4-9-30(29)16(15)18(25-19)26-20(12-28)5-1-6-20/h10-11,13,28H,1-9,12H2,(H,24,25,26)/t30-/m1/s1 |
| InChiKey | UHYCLWAANUGUMN-SSEXGKCCSA-N |
| CID | 166177189 |
| Short Description | PDE4B inhibitor |
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