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XYL-1
Axon 4241
CAS:
2946705-91-3
Purity:
98%
- Soluble in DMSO and EtOH
- MF: C19H22F6N8O2
- MW: 508.42
Description
XYL-1 is a highly potent PARP7 inhibitor with an IC50 value of 0.6 nM. Additionally, XYL-1 displayed weak inhibitory activity on PARP1 (IC50 > 1.0 μM). XYL-1 restored the type I interferon signaling pathway and facilitated T-cell infiltration into tumor tissues in CT26 tumor-bearing mice.
More Information
| Parent CAS No. | 2946705-91-3 |
|---|---|
| Chemical Name | N-(4-(6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridazin-4-ylamino)butyl)-4-(5-(trifluoromethyl)pyrimidin-2-yl)piperazine-1-carboxamide |
| MFCD | N.A. |
| Short Description | PARP7 inhibitor |
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