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KEA1-97
Axon 3744
CAS:
2138882-71-8
Purity:
99%
- Soluble in DMSO
- MF: C15H9Cl2FN4
- MW: 335.16
Description
KEA1-97 is a disruptor of the interaction of thioredoxin (TXN) with caspase 3 (IC50 value of 10 μM). KEA1-97 activates caspases, induces apoptosis without affecting TXN activity, and impairs in vivo breast tumor xenograft growth.
More Information
| Parent CAS No. | 2138882-71-8 |
|---|---|
| Chemical Name | 4,6-Dichloro-N-(4'-fluorobiphenyl-4-yl)-1,3,5-triazin-2-amine |
| SMILES | C1(Cl)N=C(NC2C=CC(C3C=CC(F)=CC=3)=CC=2)N=C(Cl)N=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C15H9Cl2FN4/c16-13-20-14(17)22-15(21-13)19-12-7-3-10(4-8-12)9-1-5-11(18)6-2-9/h1-8H,(H,19,20,21,22) |
| InChiKey | DUROVTLUQOYUPH-UHFFFAOYSA-N |
| CID | 135338301 |
| Short Description | TXN-caspase 3 disruptor |
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