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O-Desmethylvenlafaxine
- Desvenlafaxine - DVS 233
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C16H25NO2
- MW: 263.38
Description
Active metabolite of Venlafaxine (Axon 1727), a serotonin-norepinephrine reuptake inhibitor (SNRI). Racemate of Axon 1720 and 1721. Also the succinate salt is available as Axon 2116.
Other metabolites of Venlafaxine which are available from stock are:
| R-(-)-O-Desmethylvenlafaxine (Axon 1720) |
| S-(+)-O-Desmethylvenlafaxine (Axon 1721) |
| Deshydroxy Venlafaxine HCl (Axon 1722) |
| WY 45960 hydrochloride (Axon 1723) |
| WY 45494 hydrochloride (Axon 1724) |
| WY 46689 (Axon 1725) |
| Dinorvenlafaxine (Axon 1726) |
| O-Desmethylvenlafaxine succinate (Axon 2116) |
| O-Desmethylvenlafaxine (Axon 3578) |
More Information
| Parent CAS No. | 93413-62-8 |
|---|---|
| Chemical Name | 4-(2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol |
| SMILES | C1CC(O)(C(CN(C)C)C2C=CC(O)=CC=2)CCC1 |
| MFCD | MFCD00871934 |
| InChi | InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3 |
| InChiKey | KYYIDSXMWOZKMP-UHFFFAOYSA-N |
| CID | 125017 |
| Short Description | SNRI |
References
- EA Muth et al. Antidepressant biochemical profile of the novel bicyclic compound Wy-45,030, an ethyl cyclohexanol derivative. Biochem. Pharmacol. 1986, 35(24), 4493–4497.
- FP Bymaster et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacol. 2001, 25(6), 871–80.
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