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Atomoxetine hydrochloride

Axon 1297
  • Parent CAS:  83015-26-3
  • Optical Purity:  >98% e.e.
  • Soluble in water
  • MF:  C17H21NO.HCl
  • MW:  291.82

Description

Atomoxetine hydrochloride is a selective norepinephrine reuptake inhibitor (NRI/NARI) that blocks norepinephrine transporter (NET/SLC6A2)-mediated uptake.

NET inhibition increases extracellular norepinephrine and influences attention, arousal, executive function and autonomic signaling. Atomoxetine is a reference compound for noradrenergic transporter pharmacology and ADHD-related pathway studies.

Key Features

  • Selective norepinephrine reuptake inhibitor
  • Targets NET/SLC6A2-mediated uptake
  • Enhances noradrenergic neurotransmission in uptake assays
  • Useful for attention and catecholamine signaling research

Applications

  • NET uptake inhibition assays
  • Noradrenergic neurotransmission studies
  • ADHD-related pathway research
  • Monoamine transporter selectivity profiling

More Information

Parent CAS No. 83015-26-3
Chemical Name Methyl-((R)-3-phenyl-3-o-tolyloxy-propyl)-amine hydrochloride
SMILES C1(O[C@H](CCNC)C2=CC=CC=C2)C(C)=CC=CC=1.Cl |&1:2,r|
MFCD N.A.
InChi InChI=1S/C17H21NO.ClH/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15;/h3-11,17-18H,12-13H2,1-2H3;1H/t17-;/m1./s1
InChiKey LUCXVPAZUDVVBT-UNTBIKODSA-N
CID 54840
Short Description NRI inhibitor

References

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