Order

Size
Price
Stock
Qty

Optovin

Axon 2374
CAS:  348575-88-2
Purity:  99%
  • Soluble in 0.1N NaOH(aq) and DMSO
  • MF:  C15H13N3OS2
  • MW:  315.41

Description

Reversible photoactivated TRPA1 agonist (EC50 value 2 μM) that specifically activates TRPA1, but not TRPV1 or TRPM8. Optovin activates human TRPA1 via structure-dependent photochemical reactions with redox-sensitive cysteine residues, and enables control of motor activity in paralyzed extremities by localized illumination in animals. Optovin-treated animals respond to 387-nm (violet) stimuli but not to 485-nm (blue), 560-nm (green) or longer wavelengths.

More Information

Parent CAS No. 348575-88-2
Chemical Name 5-((2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one
SMILES S1/C(=C/C2C=C(C)N(C3=CC=CN=C3)C=2C)/C(=O)NC1=S
MFCD N.A.
InChi InChI=1S/C15H13N3OS2/c1-9-6-11(7-13-14(19)17-15(20)21-13)10(2)18(9)12-4-3-5-16-8-12/h3-8H,1-2H3,(H,17,19,20)/b13-7+
InChiKey YISGMOZSGOGYOU-NTUHNPAUSA-N
CID 1365101
Short Description TRPA1 agonist

Related Products

AXON ID NAME FROM PRICE
1225 U 73122

From $121.00

1251 GW 441756

From $82.50

1504 ABT 102

From $99.00

1610 AZ 23

From $88.00

1816 A 784168

From $104.50

2248 GNF 5837

From $99.00

2423 M8-B hydrochloride

From $132.00

2458 Clemizole

From $82.50

2483 PF 05105679

From $121.00

2498 RQ 00203078

From $143.00

2742 GSK 2193874

From $132.00

3348 NMDAR-TRPM4 blocker C8 dihydrochloride

From $132.00

3349 NMDAR-TRPM4 blocker C19 dihydrochloride

From $143.00

3633 Ononetin

From $66.00

3726 JT010

From $99.00

Loading...