Your cart

There are no items in your shopping cart

BMH 21

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2462

CAS [896705-16-1]

MF C21H20N4O2
MW 360.41

  • Purity: 99%
  • Soluble in 0.1N HCl (aq)

BMH 21

Description

RNA polymerase I (RNAP1) inhibitor (IC50 values 0.05 µM and 0.07 µM for degradation of RPA194 and translocation of NCL, respectively). BMH-21 intercalates with GC-rich rDNA, inhibits Pol I, and causes activation of p53 and proteasome-mediated degradation of RPA194. Furthermore, BMH21 showed broad and potent anticancer activity in NCI60 cancer cell lines and reduced tumor burden in mouse xenograft assays.
Order
Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €325.00 In Stock
Special Offers
Size Unit Price Stock
2 x 10 mg €150.00 In Stock
Need more? Bulk Inquiry

Related Products

Axon ID Name Description From price
2173 CX 5461 Inhibitor of RNA Polymerase I (RNAP1) €120.00
2855 Dolutegravir HIV integrase inhibitor €135.00
3135 Favipiravir Potent and selective inhibitor of viral RNA polymerase €70.00
3301 Sofosbuvir Potent and selective HCV NS5B polymerase inhibitor €90.00
3417 IMT1B First-in-class, potent and highly specific allosteric POLRMT inhibitor €130.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Newsletter
Give Feedback
 
Send E-mail

Customer Support

About Axon Medchem

Download Product Catalog

Download the Axon Ligands™ catalogue 2021 Spring Edition

Follow Us

© 2016 Axon Medchem. All Rights Reserved.

Send us a message

×

Contact Us

* Required Fields

Please wait...