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Axon 3417
CAS [2304621-06-3]
MF C24H21ClFNO6MW 473.88
IMT1B is a first-in-class, potent and highly specific allosteric inhibitor of the human mitochondrial RNA polymerase (POLRMT), which is essential for mtDNA transcription and biogenesis of the oxidative phosphorylation (OXPHOS) system. IMT1B shows potent effects for the treatment of cancer in preclinical mouse models.
KEYWORDS: IMT1B | Supplier | POLRMT inhibitor | LDC203974 | LDC 203974 | LDC-203974 | CAS [2304621-06-3] | DNA-RNA | RNAP1 | Inhibitor | Enzymes | OXPHOS
(S)-1-((R)-2-(4-(2-Chloro-4-fluorophenyl)-2-oxo-2H-chromen-7-yloxy)propanoyl)piperidine-3-carboxylic acid
[2304621-06-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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