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Axon 1972
CAS [871362-31-1]
MF C19H13ClF3N3OMW 391.77
Potent, orally bioavailable, long lasting and selective mGluR5 allosteric antagonist or negative allosteric modulator; CTEP binds mGluR5 with low nanomolar affinity and shows >1000-fold selectivity against other targets, including all known mGlu receptorsCTEP has considerably improved properties over older mGluR5 antagonists such as MPEP (Axon 1222) and Fenobam (Axon 1345)
KEYWORDS: CTEP | supplier | NAM of mGluR5 | RO 4956371 | RO4956371 | CAS [871362-31-1] | Glutamate | mGluR5 | NAM | allosteric modulator | mpep | fenobam | long lasting
2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine
[871362-31-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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