VU0360172 hydrochloride

Based on 21 reference(s) in Google Scholar 8 10 21

Axon 3421

CAS [1309976-62-2]

MF C18H15FN2O.HCl
MW 330.78

  • Purity: 98%
  • Soluble in DMSO and EtOH
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VU0360172 hydrochloride

Description

VU0360172 hydrochloride is a selective, orally active mGluR5 PAM with an EC50 value of 16 nM and a Ki value of 195 nM. VU0360172 hydrochloride produced a dose-dependent reversal of amphetamine-induced hyperlocomotion, a rodent model predictive of antipsychotic activity.

KEYWORDS: VU0360172 hydrochloride | Supplier | mGluR5 PAM | VU 0360172 hydrochloride | VU-0360172 hydrochloride | CAS [1309976-62-2] | [1310012-12-4] | Glutamate | mGluR5 | PAM | Receptors | Anxiety | Schizophrenia

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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