Fenobam - MCN 3377-98 | NPL 2009

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1345

CAS [57653-26-6]

MF C11H11ClN4O2
MW 266.68

  • Purity: 99%
  • Soluble in DMSO

Fenobam

Description

Potent and selective antagonist for metabotropic glutamate receptor subtype 5 (mGluR5)
CTH Friedmann et al. Phase II double-blind controlled study of a new anxiolytic, fenobam (McN-3377) vs placebo. Curr. Ther. Res. 1980, 27, 144-151.
 
Porter et al. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J. Pharmacol. Exp. Ther. 2005, 315, 711.
mGluR5 antagonist

Chemical name

1-(3-Chloro-phenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)-urea

Parent CAS No.

[57653-26-6]

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10 mg €66.00 In Stock
50 mg €266.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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