Based on 111 reference(s) in Google Scholar 8 10 111

Axon 2691

CAS [170846-74-9]

MW 201.61

  • Purity: 98%
  • Soluble in DMSO



The mGluR5 receptor agonist CHPG selectively activates mGluR5a receptors (EC50 value of 750 μM), compared to mGluR1α receptors, when expressed in CHO cells. CHPG also potentiates NMDA-induced depolarizations in rat hippocampal slices, and is suggested to act directly on mGluR5 in dopaminergic neurons to induce the release of DA. Also CHPG promotes proliferation of human embryonic cortical NSCs with activation of the MAPKs signaling pathway.

KEYWORDS: CHPG | supplier | mGluR5 agonist | CAS [170846-74-9] | Glutamate | mGluR5 | Agonist | Receptors | CAS [1303993-73-8] | CHO | Hippocampus

Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €345.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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