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MG 132 - Z-Leu-leu-leu-al

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1869

CAS [133407-82-6]

MF C26H41N3O5
MW 475.62

  • Purity: 98%
  • Optical purity: Optically pure
  • Soluble in DMSO

MG 132

Description

Specific, potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM). MG132 inhibits NF-κB activation with an IC50 of 3 µM and prevents β-secretase cleavage. MG132 also activates c-Jun N-terminal kinase (JNK1), which initiates apoptosis.
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Size Unit Price Stock
10 mg €80.00 In Stock
50 mg €240.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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