FLAT

FAAH-like anandamide transporter (FLAT) is a partly cytosolic variant of the intracellular anandamide-degrading enzyme, fatty acid amide hydrolase-1 (FAAH-1), which lacks amidase activity but binds anandamide with low micromolar affinity and facilitates its translocation into cells. The functional properties of FLAT suggest that this protein is a key molecular component of the anandamide transport system in neural cells, and a potential target for therapeutic drugs[1].


[1] J Fu et al. A catalytically silent FAAH-1 variant drives anandamide transport in neurons. Nat Neurosci. 2011 Nov 20;15(1):64-9.

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Axon ID Name Description From price
2941 ARN 272 Selective inhibitor of FAAH-like anandamide transporter (FLAT)  Recently added €90.00

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