FLAT

FLAT

FAAH-like anandamide transporter (FLAT) is a partly cytosolic variant of the intracellular anandamide-degrading enzyme, fatty acid amide hydrolase-1 (FAAH-1), which lacks amidase activity but binds anandamide with low micromolar affinity and facilitates its translocation into cells. The functional properties of FLAT suggest that this protein is a key molecular component of the anandamide transport system in neural cells, and a potential target for therapeutic drugs.

Read More
sort-descending
  • ARN 272
    2941
    ARN 272
    The price depends on the options chosen on the product page

    From $99.00

1 Item

More About FLAT

FAAH-like anandamide transporter (FLAT) is a partly cytosolic variant of the intracellular anandamide-degrading enzyme, fatty acid amide hydrolase-1 (FAAH-1), which lacks amidase activity but binds anandamide with low micromolar affinity and facilitates its translocation into cells. The functional properties of FLAT suggest that this protein is a key molecular component of the anandamide transport system in neural cells, and a potential target for therapeutic drugs[1].

[1] J Fu et al. A catalytically silent FAAH-1 variant drives anandamide transport in neurons. Nat Neurosci. 2011 Nov 20;15(1):64-9.

Loading...