eIF4A i28

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 4120

CAS [2861994-92-3]

MF C24H20N2O5
MW 416.43

  • Purity: 98%
  • Soluble in DMSO

eIF4A i28


eIF4A i28 is a RNA-competitive, ATP-uncompetitive eIF4A inhibitor with an IC50 of 8.6 μM. eIF4A i28 binds a novel pocket in the RNA groove and inhibits eIF4A with a novel mechanism in which it perturbs RNA binding, blocks the hydrolysis of ATP, and consequently inhibits RNA helicase activity.

Keywords: eIF4A i28 | Supplier | eIF4A inhibitor | eIF4Ai28 | eIF4A-i28 | CAS [2861994-92-3] | DNA-RNA | Helicase-Primase | Inhibitor | Enzymes | ATP-powered DEAD-box RNA-helicase | Eukaryotic initiation factor (eIF)4A

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5 mg €100.00 In Stock
25 mg €350.00 In Stock
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Size Unit Price Stock
2 x 5 mg €160.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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