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Products
Enzymes
Transferases
Kinases (Serine-Threonine Specific Protein)
p90-RSK
LJI308

LJI308

Based on 10 reference(s) in Google Scholar 8 10 10

Axon 3991

CAS [1627709-94-7]

MF C21H18F2N2O2
MW 368.38

Purity: 99%
Soluble in DMSO and EtOH

LJI308

Description

LJI308 is a potent and specific pan-RSK inhibitor with IC50 values of 6 nM, 4 nM and 13 nM for RSK1, RSK2 and RSK3, respectively.

Keywords: LJI308 | Supplier | RSK inhibitor | LJI 308 | LJI-308 | CAS [1627709-94-7] | [1803574-29-9] | Non Selective (Ribosomal proteins) | p90-RSK | Inhibitor | Enzymes | p90 ribosomal S6 kinase

R Jain et al. Discovery of Potent and Selective RSK Inhibitors as Biological Probes. J Med Chem. 2015 Sep 10;58(17):6766-83.

I Aronchik et al. Novel potent and selective inhibitors of p90 ribosomal S6 kinase reveal the heterogeneity of RSK function in MAPK-driven cancers. Mol Cancer Res. 2014 May;12(5):803-12.

Cell Signaling & Oncology EC 2.7.11.1 p90-RSK

Potent RSK inhibitor (p90 RSK specific)

Chemical name

2,6-Difluoro-4-(4-(4-morpholinophenyl)pyridin-3-yl)phenol

Parent CAS No.

[1627709-94-7]

Order

Size	Unit Price	Stock
5 mg	€130.00	In Stock
25 mg	€490.00	In Stock

Need more? Bulk Inquiry

Related Products

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1528	BI-D1870	RSK inhibitor (p90 RSK specific)		€80.00
1848	FMK	RSK inhibitor (p90 RSK specific)		€75.00
3328	APIO-EE-07	Dual RSK1/MSK2 inhibitor		€140.00

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