CASIN - Pirl1-related compound 2

Based on 140 reference(s) in Google Scholar 8 10 140

Axon 3987

CAS [425399-05-9]

MF C20H22N2O
MW 306.40

  • Purity: 99%
  • Soluble in 0.1N HCl(aq), DMSO and EtOH



CASIN is a selective Cdc42 activity inhibitor. Treatment with CASIN (5µM) reduced the elevated level of active Cdc42 observed in aged primitive hematopoietic cells to the level observed in young cells. CASIN treatment did not alter cell cycle status or apoptosis in aged LT-HSCs. In response to treatment with CASIN, LT-HSCs from aged mice showed a dose-dependent increase in the percentage of polarized cells, becoming progressively indistinguishable from young cells.

KEYWORDS: CASIN | Supplier | Cdc42 inhibitor | Pirl1-related compound 2 | CAS [425399-05-9] | [1219188-29-0] | Cytoskeleton | CDC42 | Inhibitor | Enzymes | Pirl1 | RhoGTPase Cdc42 | Stem cell aging

Size Unit Price Stock
10 mg €140.00 In Stock
50 mg €490.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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