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Axon 3854
CAS [2097132-94-8]
MF C27H32FN9O2MW 533.60
BLU-667 is a highly potent and selective RET inhibitor with an IC50 value of 0.4 nM. In vivo, BLU-667 potently inhibited growth of NSCLC and thyroid cancer xenografts driven by various RET mutations and fusions without inhibiting VEGFR2.
KEYWORDS: BLU-667 | Supplier | RET inhibitor | Pralsetinib | RG 6396 | BLU667 | BLU 667 | RG6396 | RG 6396 | X 581238 | X581238 | CAS [2097132-94-8] | GDNF | RET | Inhibitor | Receptors
(1s,4R)-N-((S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-1-methoxy-4-(4-methyl-6-(5-methyl-1H-pyrazol-3-ylamino)pyrimidin-2-yl)cyclohexanecarboxamide
[2097132-94-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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