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Ervogastat

 - PF06865571
Axon 3823
CAS:  2186700-33-2
  • Optical Purity:  100% e.e.
  • Soluble in DMSO and EtOH
  • MF:  C21H21N5O4
  • MW:  407.42

Description

Ervogastat is a first-in-class potent and selective inhibitor of diacylglycerol acyltransferase 2 (DGAT-2) with an IC50 value of 17.2 nM.

More Information

Parent CAS No. 2186700-33-2
Chemical Name (S)-2-(5-(3-Ethoxypyridin-2-yloxy)pyridin-3-yl)-N-(tetrahydrofuran-3-yl)pyrimidine-5-carboxamide
SMILES C1(OC2C(OCC)=CC=CN=2)C=C(C2N=CC(C(=O)N[C@H]3CCOC3)=CN=2)C=NC=1 |&1:20,r|
MFCD N.A.
InChi InChI=1S/C21H21N5O4/c1-2-29-18-4-3-6-23-21(18)30-17-8-14(9-22-12-17)19-24-10-15(11-25-19)20(27)26-16-5-7-28-13-16/h3-4,6,8-12,16H,2,5,7,13H2,1H3,(H,26,27)/t16-/m0/s1
InChiKey UKBQFBRPXKGJPY-INIZCTEOSA-N
CID 134262752
Short Description DGAT-2 inhibitor

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