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Axon 3790
CAS [303094-67-9]
MF C14H14F3N5MW 309.29
ZINC69391 is a specific Rac1 inhibitor. ZINC69391 was able to block Rac1 interaction with its GEF Tiam1, prevented EGF-induced Rac1 activation and inhibited cell proliferation, cell migration and cell cycle progression in highly aggressive breast cancer cell lines. Moreover, ZINC69391 inhibited lung metastasis in vivo.
KEYWORDS: ZINC69391 | Supplier | Rac1-GEF inhibitor | ZINC 69391 | ZINC-69391 | CAS [303094-67-9] | Cytoskeleton | Rac | Inhibitor | Enzymes | Breast cancer
1-(4,6-Dimethylpyrimidin-2-yl)-3-(2-(trifluoromethyl)phenyl)guanidine
[303094-67-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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