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STING activator C53
Axon 3673
CAS:
2259624-71-8
Purity:
99%
- Soluble in DMSO
- MF: C25H19ClF4N2O2
- MW: 490.88
Description
STING activator C53 demonstrated robust on-target functional activation of STING (EC50 value of 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.
More Information
| Parent CAS No. | 2259624-71-8 |
|---|---|
| Chemical Name | 1-(2-Chloro-6-fluorobenzyl)-3,3-dimethyl-2-oxo-N-(2,4,6-trifluorobenzyl)indoline-6-carboxamide |
| SMILES | C1C(F)=C(CNC(=O)C2C=C3N(CC4C(F)=CC=CC=4Cl)C(=O)C(C)(C)C3=CC=2)C(F)=CC=1F |
| MFCD | N.A. |
| InChi | InChI=1S/C25H19ClF4N2O2/c1-25(2)17-7-6-13(23(33)31-11-15-20(29)9-14(27)10-21(15)30)8-22(17)32(24(25)34)12-16-18(26)4-3-5-19(16)28/h3-10H,11-12H2,1-2H3,(H,31,33) |
| InChiKey | OEBVYNULNKSONR-UHFFFAOYSA-N |
| CID | 137367538 |
| Short Description | STING agonist |
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