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CU-76

Axon 4118
CAS:  2400954-58-5
Purity:  99%
  • Soluble in DMSO and EtOH
  • MF:  C11H8F2IN5O2
  • MW:  407.12

Description

CU-76 is a human cGAS (hcGAS) inhibitor with high binding affinity (IC50 value of 0.24 µM). CU-76 selectively inhibits the DNA pathway in human cells but has no effect on the RIG-I-MAVS or Toll-like receptor pathways.

More Information

Parent CAS No. 2400954-58-5
Chemical Name Methyl 4-amino-6-(3,5-difluoro-4-iodophenylamino)-1,3,5-triazine-2-carboxylate
Short Description hcGAS inhibitor

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