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CU-76
- Soluble in DMSO and EtOH
- MF: C11H8F2IN5O2
- MW: 407.12
Description
CU-76 is a human cGAS (hcGAS) inhibitor with high binding affinity (IC50 value of 0.24 µM). CU-76 selectively inhibits the DNA pathway in human cells but has no effect on the RIG-I-MAVS or Toll-like receptor pathways.
More Information
| Parent CAS No. | 2400954-58-5 |
|---|---|
| Chemical Name | Methyl 4-amino-6-(3,5-difluoro-4-iodophenylamino)-1,3,5-triazine-2-carboxylate |
| Short Description | hcGAS inhibitor |
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