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Featured Products
Axon 3668
CAS [2719793-90-3]
MF C18H20N4O2MW 324.38
RP-6306 is a first-in-class, potent, selective, and orally bioavailable PKMYT1 (or MYT1) inhibitor with IC50 values of 0.014 μM and 0.002 μM in cell and nanoBRET assays, respectively. RP-6306 is the active (aS)-atropisomer of the racemate. Its opposite atropisomer, (aR)-RP-6306 (Axon 3759), is also available.In a recent study, Wee1 inhibitor MK-1775 (Axon 1494) and MYT1 inhibitor RP-6306 (Axon 3668) combination treatment showed synergistic cell killing in a panel of cancer cell lines. Wee1 and MYT1 combined inhibition might be a potential cancer therapeutic strategy.
KEYWORDS: RP-6306 | Supplier | PKMYT1 inhibitor | Lunresertib | RP6306 | RP 6306 | CAS [2719793-90-3] | Cyclin dependent (CDK) | Wee1 | Inhibitor | Enzymes | CDK | Protein kinase | Membrane-associated tyrosine/threonine 1 | Ovarian cancer
(S)-2-Amino-1-(3-hydroxy-2,6-dimethyl-phenyl)-5,6-dimethylpyrrolo[2,3-b]pyridine-3-carboxamide
[2719793-90-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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