SGC-SMARCA-BRDVIII

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 3623

CAS [1997319-84-2]

MF C19H25N5O3
MW 371.43

  • Purity: 99%
  • Soluble in 0.1N HCl(aq), DMSO and EtOH
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SGC-SMARCA-BRDVIII

Description

SGC-SMARCA-BRDVIII is a potent, highly selective and cell-active SMARCA2/4 and PB1(5) bromodomain inhibitor with Kd values of 35, 36 and 13 nM, respectively. SGC-SMARCA-BRDVIII blocked adipogenesis of 3T3-L1 murine fibroblasts by reducing the mRNA levels of key markers of adipocyte differentiation, PPARγ,C/EBPα, and FABP4.

KEYWORDS: SGC-SMARCA-BRDVIII | Supplier | SMARCA2/4/PB1(5) inhibitor | CAS [1997319-84-2] | Histone | SMARCA | PB1 | Inhibitor | Proteins | Cell differentiation | Adipogenesis | BRD family VIII | BRM | BRG1 | polybromo-1 | BAF180

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5 mg €90.00 In Stock
25 mg €320.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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