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GSK2837808A

Based on 9 reference(s) in Google Scholar 8 10 9

Axon 3621

CAS [1445879-21-9]

MF C31H25F2N5O7S
MW 649.62

Purity: 98%
Soluble in DMSO

GSK2837808A

Description

GSK2837808A is a potent, selective and NADH-competitive inhibitor of LDH-A with an IC50 value of 0.0026 μM.

KEYWORDS: GSK2837808A | Supplier | LDH-A inhibitor | GSK 2837808A | GSK-2837808A | CAS [1445879-21-9] | Lactate | LDH | Inhibitor | Enzymes | Hepatocellular carcinoma | Breast carcinoma | Aerobic glycolysis

J Billiard et al. Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells. Cancer Metab. 2013 Sep 6;1(1):19.

D Annas et al. Synthesis and initial screening of lactate dehydrogenase inhibitor activity of 1,3-benzodioxole derivatives. Sci Rep. 2020 Nov 16;10(1):19889.

Apoptosis Cell Signaling & Oncology LDH EC 1.1.1.27

Potent, selective and NADH-competitive inhibitor of LDH-A

Chemical name

3-(3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-ylamino)-5-(3,5-difluorophenoxy)benzoic acid

Parent CAS No.

[1445879-21-9]

Order

Size	Unit Price	Stock
5 mg	€130.00	In Stock
25 mg	€460.00	In Stock

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2450	NHI 2	Selective cell membrane permeable inhibitor of human lactate dehydrogenase A		€90.00

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