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Telaglenastat - CB-839

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3532

CAS [1439399-58-2]

MF C26H24F3N7O3S
MW 571.57

  • Purity: 99%
  • Soluble in DMSO

Telaglenastat

Description

Telaglenastat is a potent, selective, and orally bioavailable inhibitor of both splice variants of glutaminase (KGA and GAC). Furthermore, Telaglenastat promoted a tumor-specific pharmacodynamic response and had in vivo efficacy in breast cancer xenograft models, both as a single agent and in combination with the standard-of-care agent paclitaxel.

KEYWORDS: Telaglenastat | Supplier | Glutaminase inhibitor | CB-839 | CB839 | CB 839 | CAS [1439399-58-2] | [1874231-60-3] | Glutamine | Glutaminase | Inhibitor | Enzymes | Triple-negative breast cancer | TNBC

Potent, selective, and orally bioavailable glutaminase inhibitor

Chemical name

2-(Pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol-2-yl)acetamide

Parent CAS No.

[1439399-58-2]

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Size Unit Price Stock
10 mg €70.00 In Stock
50 mg €220.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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