GSK2795039

Based on 29 reference(s) in Google Scholar 80 10 29

Axon 3526

CAS [1415925-18-6]

MF C23H26N6O2S
MW 450.56

  • Purity: 99%%
  • Soluble in 0.1N NaOH(aq), DMSO and EtOH
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GSK2795039

Description

GSK2795039 is a potent and selective NADPH oxidase 2 (NOX2) inhibitor. GSK2795039 inhibited both the formation of ROS and the utilization of the enzyme substrates, NADPH and oxygen, in a variety of semirecombinant cell-free (with pIC50 values in the range of 6.18 to 6.60) and cell-based NOX2 assays.

KEYWORDS: GSK2795039 | Supplier | NOX2 inhibitor | GSK 2795039 | GSK-2795039 | CAS [1415925-18-6] | NADPH | Inhibitor | Enzymes | NOX | Oxidative stress

Potent and selective NOX2 inhibitor

Chemical name

N-(1-Isopropyl-3-(1-methylindolin-6-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-methyl-1H-pyrazole-3-sulfonamide

Parent CAS No.

[1415925-18-6]

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5 mg €150.00 In Stock
25 mg €500.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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