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Axon 3482
CAS [2407782-01-6]
MF C20H19N3O3MW 349.38
LDC7559 inhibits the NOX2-dependent oxidative burst in neutrophils by activating the glycolytic enzyme phosphofructokinase-1 liver type (PFKL) and dampening flux through the pentose phosphate pathway. LDC7559 is an inhibitor of NOX2-dependent NETosis with an IC50 value of 3.1 μM.
KEYWORDS: LDC7559 | Supplier | PFKL activator | LDC 7559 | LDC-7559 | CAS [2407782-01-6] | Fructose 6-phosphate | PFK | Activator | Enzymes | Phosphofructokinase-1 liver type | PFKL | NADPH oxidase | Gasdermin D | GSDMD | Phagocytic oxidative burst
N-(2-(2-Methoxyphenyl)-4,10-dihydrobenzo[f]pyrazolo[5,1-c][1,4]oxazepin-7-yl)acetamide
[2407782-01-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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