trans-Clovamide is a naturally occurring caffeoyl conjugate and a potent antioxidant. trans-Clovamide is able to protect neurons from injury in three in vitro models of neuronal death: oxidative stress, excitotoxicity and OGD/reoxygenation. Moreover, trans-Clovamide is a powerful oxygen radical scavenger, partially contributed by its molecular catechol moieties. Also, trans-Clovamide is believed to exhibit preventive effects on Aβ aggregation.

KEYWORDS: trans-Clovamide | Supplier | Antioxidant | CAS [53755-02-5] | Non Selective | Modulator | Alzheimer's disease | Aβ aggregation | Neuroprotectant